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A SYSTEM WHICH CAN “TUNE” DRUGS
TO PERFECT THEM INTO MORE POTENCY

ABOUT THE PROJECT

Traditionally our research is focused to organic and hybrid systems used as dyes, indicators, sensing and NLO materials. Molecular spectroscopy (UV-Vis-NIR, IR/ Raman, fluorescence, NMR and mass spectrometry) and quantum chemistry are used as tools.In other words we are on the border between physical organic and organic analytical chemistry, depending on the viewpoint.

 
 
 
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ABOUT THE TEAM

Inter and IntraMolecular Processes (I2MP) Group has been created in 2007 after the group leader had been appointed as Senior Research Associate in Organic Chemistry at The Institute of Organic Chemistry with Center of Phytochemistry, Bulgarian Academy of Sciences. The group continues the development of The UV-Vis Spectroscopy and Chemometrics Group (National Forestry University, Sofia).

GROUP MEMBERS

Liudmil Antonov

Dr Vera Deneva

Dr Atanas Kurutos

Yana Manolova

Nevse Molla

Dinko Stoikov

Silvia Hristova

Daniela Ivanova

Nikola Dimitrov

Research Director

Assistant Professor

Assistant Professor

Assistant Professor

PhD student (1st year)

PhD student (1st year)

MSc student (Sofia University)

MSc student (Sofia Medical University)

BSc student (Sofia University)

ALUMNI

Vesselin Petrov, PhD student (Spectroscopy/Chemometrics),

currently at University of Lisboa, Portugal

Sonya Damyanova, Collaborator (Ecology),

currently at University of Forestry, Bulgaria

Maya Nikiforova, PhD student (Optical sensors),

currently at DansPharma, Bulgaria

Boriana Cavicchia, MSc student (Tautomeric dyes),

currently at American Red Cross

Dimitar Dimitrov, MSc student (Aggregation of Dyes)

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LIUDMIL ANTONOV, PHD, DRSCI

Bulgarian Academy of Sciences

BAS · Emil Djakov Institute of Electronics

Liudmil Antonov currently works at the Institute of Organic Chemistry with Centre of Phytochemistry, Bulgarian Academy of Sciences. Liudmil does research in Analytical Chemistry, Physical Organic Chemistry and Spectroscopy. The current projects are based on the tautomerism of organic compounds.

MEMBERSHIPS

  • European Photochemical Association

  • Tokyo Institute of Technology Alumni Association

  • Bulgarian Humboldt Union

  • Union of Scientists in Bulgaria

RESEARCH INTERESTS

Quantum chemistry

(relative stability of equilibrium systems, solvent effects, absorption and emission spectra prediction)

 

Molecular Spectroscopy

(UV-Vis-NIR, fluorescence, mass spectrometry)

 

Chemometrics

(including derivative spectroscopy and overlapping bands fitting)

 

Tautomerism

(experimentally and computationally)

 

Supramolecular chemistry

(host-guest interactions, molecular switches and wires, sensoring systems)

 

Dye chemistry

(design and properties – photochromism, thermochromism, halochromism, solvatochromism, aggregation)

COLLABORATIONS

Prof. Mariana Mitewa

(University of Sofia, Faculty of Chemistry, since 1992) – coordination chemistry

Prof. Susumu Kawauchi

(Tokyo Tech, Department of Organic and Polymeric Materials, since 1995) – quantum chemistry

Prof. Poul Erik Hansen and Dr. Fadhil S. Kamounah

(University of Roskilde, Department of Science, Systems and Models, since 1997) - tautomerism of Schiff bases

Prof. Walter M.F. Fabian 

(University of Graz, Institute of Chemistry, since 1998) – tautomerism

Prof. Gert van der Zwan 

(Vrije University Amsterdam, Department of Chemistry and Pharmaceutical Sciences, since 1998) - proton transfer

 

Prof. Koji Ohta and Dr. Kenji Kamada 

(National Institute of Advanced Industrial Science and Technology, Research Institute for Ubiquitous Energy Devices, since 2002) - NLO materials

Prof. Jakob Wirz 

(Univertsity of Basel, Departement Chemie, since 2005) – flash photolysis

Prof. Katharina M. Fromm 

(University of Fribourg, Chemistry Department, since 2007) - crystallography

Prof. Stefan Lochbrunner 

(University of Rostock, Institute of Physics, since 2011) – dynamics of proton transfer

Prof. Christoph Schalley 

(Free University of Berlin, Institute of Chemistry and Biochemistry, since 2012) – supramolecular chemistry

Prof. Carlo Adamo

(ParisTech, since 2014) – excited state proton transfer

 

 

SOFTWARE

STEP BY STEP FILTER

Smart approach to increase the information, which can be extracted by using derivative spectroscopy

FISHING-NET ALGORITHM

Program for resolution of overlapping bands and quantitative spectral analysis of undefined (with unknown individual spectra of the components) mixtures

MARCUS FITTING

Program for resolution of charge transfer absorption/ emission bands

 

CONTACT US

ONE JLT Tower 14th floor

Jumeriah Lake Towers, Dubai, 103805

United Arab Emirates

Disclaimer
This Website contains statements, names and references, but not limited to past or forward-looking events or features.
Potential risks and uncertainties include factors as general usage, implementation or applications restricted by laws and regulations are part of the disclaimers.

 

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